1-BOC-ISONIPECOTIC ACID HYDRAZIDE
1-BOC-ISONIPECOTIC ACID HYDRAZIDE
CAS: 187834-88-4
Molecular Formula: C11H21N3O3
1-BOC-ISONIPECOTIC ACID HYDRAZIDE - Names and Identifiers
1-BOC-ISONIPECOTIC ACID HYDRAZIDE - Physico-chemical Properties
| Molecular Formula | C11H21N3O3 |
| Molar Mass | 243.3 |
| Density | 1.147±0.06 g/cm3(Predicted) |
| Melting Point | 104-106°C |
| Boling Point | 409.2±34.0 °C(Predicted) |
| Flash Point | 201.291°C |
| Vapor Presure | 0mmHg at 25°C |
| pKa | 13.01±0.20(Predicted) |
| Storage Condition | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C |
| Refractive Index | 1.508 |
1-BOC-ISONIPECOTIC ACID HYDRAZIDE - Risk and Safety
| Risk Codes | 22 - Harmful if swallowed |
| Hazard Class | IRRITANT |
1-BOC-ISONIPECOTIC ACID HYDRAZIDE - Reference Information
| uses | ethyl N-Boc-4-piperidine formate is a key intermediate in the synthesis of sodium channel blockers, which is used to treat stroke patients. It is also used as a key intermediate in the preparation of tumor necrosis factor converting enzyme inhibitors. It is also a key intermediate for the synthesis of 1-BOC-4-piperidinyl hydrazide. |
| Preparation | Using N-Boc-4-piperidine ethyl formate or N-Boc-4-piperidine methyl formate as the starting material, it is combined with hydrazine hydrate or bis-(1H-Imidazol-2-yl)-methanone is reacted to prepare the target compound 1-BOC-4-piperidinylhydrazine [1]. The synthesis reaction formula of 1-BOC-4-piperidinylhydrazide is as follows: fig. 1 the synthesis reaction formula of 1-BOC-4-piperidinylhydrazide |
Last Update：2024-04-09 02:00:07
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